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Suk Jin Kang 1 Article
Systemic Plasmacytosis: A Case Report with a Review of the Literature.
Sung Hak Lee, Chang Young Yoo, Ji Han Jung, Jin Young Yoo, Suk Jin Kang, Chang Suk Kang
Korean J Pathol. 2011;45(6):632-638.
DOI: https://doi.org/10.4132/KoreanJPathol.2011.45.6.632
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AbstractAbstract PDF
Systemic plasmacytosis is an uncommon disorder characterized by widely disseminated macular skin eruptions composed of polyclonal lymphoplasmacytic infiltrates associated with variable extracutaneous involvement. An aggressive clinical course has been observed in a small number of patients, but most cases have followed chronic and benign clinical course without spontaneous remission. Previously reported cases of this entity have been described almost exclusively in Japanese patients. We recently experienced a case of systemic plasmacytosis in a 48-year-old Korean female patient. Initial skin biopsy specimen revealed patchy perivascular and periadnexal infiltrates of mature plasma cells. Serum immunoelectrophoresis revealed polyclonal hypergammaglobulinemia, and polyclonal plasmacytosis was noted on the subsequent biopsy specimens of left supraclavicular and axillary lymph nodes. Multiple tiny pulmonary nodules appeared six years after the initial cutaneous presentation and were found to be of the same histologic appearance. We herein report a rare case of systemic plasmacytosis with a review of the literature.

Citations

Citations to this article as recorded by  
  • Cutaneous plasmacytosis with mast cell infiltration
    Sarina Jain, RohitV Hede, UdayS Khopkar
    Indian Journal of Dermatology, Venereology and Leprology.2020; 86(1): 91.     CrossRef
  • Plasmocitosis cutánea en un varón de raza blanca
    A. López-Gómez, T. Salas-García, A. Ramírez-Andreo, E. Poblet-Martínez
    Actas Dermo-Sifiliográficas.2015; 106(6): 520.     CrossRef
  • Cutaneous Plasmacytosis in a White Man
    A. López-Gómez, T. Salas-García, A. Ramírez-Andreo, E. Poblet-Martínez
    Actas Dermo-Sifiliográficas (English Edition).2015; 106(6): 520.     CrossRef

J Pathol Transl Med : Journal of Pathology and Translational Medicine